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Bowen University

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Akingbolabo Daniel OGUNLAKIN

Research Fellow I
college of AGRICULTURE, ENGINEERING AND SCIENCE (COAES)
Biochemistry Programme

A lecturer in Biochemistry programme, Bowen University, Iwo. Osun state. He also holds a Bachelor of Science Honours degree from Olabisi Onabanjo University, Ago Iwoye, Ogun State and M.Sc. as well as Ph.D degrees in Pharmacognosy from university of Ibadan. He emerged as one of the best students in her MSc class in Department of Pharmacognosy with a Ph.D grade where he completed her doctoral programme as well.

Dr Akingbolabo D. Ogunlakin worked on indigenous medicinal plants from Nigerian ethnomedicine with anti- polycystic ovarian syndrome (PCOS) effect (via in vivo, in vitro and in silico models). He designed an in vitro approach for PCOS assay. He hopes to explore phytochemical methods to investigate the safety and efficacy of the phytomedicines commonly used in Nigeria in order to provide scientific validation on their medicinal claims. Dr Akingbolabo D. Akingbolabo grasp new concepts with ease and is endowed with a very inquisitive mind. He is highly focused character with an insatiable thirst for knowledge.

Education
  • Ph.D. (Pharmacognosy), University of Ibadan, Ibadan. Oyo State (2021)
  • M.Sc. (Pharmacognosy), University of Ibadan, Ibadan. Oyo State (2015)
  • B.Sc. (Ind. chemistry), Olabisi Onabanjo University, Ago Iwoye. Ogun State (2010)
Research

Phytochemistry;
Biochemistry;
Pharmacognosy;
Herbal medicine formulation

Institutional Service
  • Member, Student Disciplinary committee.
Professional Service
  • Reviewer. Tropical Journal of Natural Product Research (SCOPUS, Q3)
  • Reviewer. Biomed Research International. Hindawi (SCOPUS, Q2)
  • Reviewer. Plant Science today (SCOPUS, Q4)
  • Reviewer. Trends in Phytochemical Research (SCOPUS, Q3)
  • Reviewer. Journal of Applied Pharmaceutical Science (SCOPUS, Q2)
  • Reviewer. Pharmacognosy Journal (SCOPUS, Q3)
  • Reviewer, Informatics in Medicine Unlocked (SCOPUS, Q2)
  • Reviewer, Pharmacognosy Journal (SCOPUS, Q3)
  • Reviewer, Toxicology Report (SCOPUS, Q1)
  • Reviewer, PLoS One (SCOPUS, Q1)
  • Editorial member, Advances in Biochemistry.
  • Life member, Asian Network of Research on Antidiabetic Plants (ANRAP) Society
  • Member, American Society of Pharmacognosy
  • Member, Nigerian Society of Pharmacognosy
  • Associate Member, Royal Society of Chemistry
Selected Publications
  1. Akingbolabo D. Ogunlakin, Mubo A. Sonibare, Oloruntoba E. Yeye, Almas Jabeen, Syeda Farah Shah, Oluwafemi Adeleke Ojo, Gideon Ampoma Gyebi, Damilare IyinKristi Ayokunle (2023) Design, synthesis, and characterization of cinnamic acid derivatives with two novel acrylohydrazones on HeLa and CHO-1 cancer cell lines: The experimental and computational perspective. Chemistry Africa. https://doi.org/10.1007/s42250-023-00770-9
  2. Ogunlakin AD, Odugbemi AI, Omolekan T, Adaramoye OA, Abiola OO, Akinola A, Akinsete A, Alabi T, Alade FF, Ahossinme HE, Ajiboye A. Elemental and In vitro Antioxidant Studies of Some Bracharia species and Milk from Bowen University Dairy Farm. InIOP Conference Series: Earth and Environmental Science 2023 Aug 1 (Vol. 1219, No. 1, p. 012003). IOP Publishing.
  3. Ogunlakin AD, Sonibare MA (2023) Ameliorative effect of Kigelia africana (Lam.) Benth. fruit in letrozole-induced polycystic ovarian syndrome rat. Kuwait Journal of Science (Accepted)
  4. Ogunlakin AD, Oluwafemi Adeleke Ojo, Matthew Iyobhebhe, Toluwanimi Lemuel Ajisafe, Emmanuel Olatunbosun Adeoye, Damilare Iyinkristi Ayokunle, Mubo Adeola Sonibare, Owoola Azeezat Ambali, Great Oluwamayokun Adebodun (2023). Sodium 3-phenylpropanoate alleviate oxidative stress and iron-induced testicular toxicity in Wistar rats. Journal of Applied Pharmaceutical Science (Accepted).
  5. Ojo OA, Ogunlakin AD, Gyebi GA, Ayokunle DI, Odugbemi AI, Babatunde DE, Adenike Ajayi-Odoko O, Iyobhebhe ME, Chukwuemeka Ezea S, Akintayo OC, Ayeleso A. (2023) GC-MS chemical profiling, antioxidant, anti-diabetic, and antiinflammatory activities of Ethyl Acetate Fraction of Spilanthes filicaulis (Schumach. & Thonn.) CD Adams Leaves: Experimental and Computational Studies. Frontiers in Pharmacology.;14:1235810.
  6. Ogunlakin AD, Taiwo Rukayat Onifade, Oluwafemi Adeleke Ojo, Enitan O. Adesanya, Godwin A. Berena, Peluola Olujide Ayeni, Tolulope Omotope Omolekan, Mojisola A. Fategbe, Matthew Akin Ogunlakin, Damilare Iyinkristi Ayokunle, Mubo Adeola Sonibare (2023) A Focused Review on Antidiabetic Potential of Carica papaya L. and its constituents: From Folkloric Uses to Products Development. Bioactive Compounds in Health and Diseases 6(6):128-144
  7. Ojo OA, Ibrahim HS, Rotimi DE, Ogunlakin AD, Ojo AB. Diabetes mellitus: From molecular mechanism to pathophysiology and pharmacology. Medicine in Novel Technology and Devices. 2023 Jun 17:100247.
  8. Oluwafemi Adeleke Ojo, Hannah Sokolayam Ibrahim, Damilare Emmanuel Rotimi, Akingbolabo Daniel Ogunlakin, Adebola Busola Ojo (2023) Diabetes mellitus: From molecular mechanism to pathophysiology and pharmacology. Medicine in Novel Technology and Devices 19: 100247. doi.org/10.1016/j.medntd.2023.100247
  9. Ojo OA, Nwafor-Ezeh PI, Rotimi DE, Iyobhebhe M, Ogunlakin AD, Ojo AB (2023). Apoptosis, inflammation, and oxidative stress in infertility: A mini review. Toxicology Reports. http://doi.org/10.1016/j.toxrep.2023.04.006.
  10. Ogunlakin AD and Mubo Adeola Sonibare (2023) Antioxidant and Ameliorative Effects of Basella alba L. On Letrozole-Induced Polycystic Ovarian Syndrome in Rats. Tropical Journal of Natural Product Research. 7(4), 2817–2822. http://www.doi.org/10.26538/tjnpr/v7i4.25.
  11. Ogunlakin AD, Taiwo Rukayat Onifade, Gideon Ampoma Gyebi, Blessing Ariyo Obafemi, Oluwafemi Adeleke Ojo (2023) In Silico Pharmacology and Bioavailability of Bioactive Constituents from Triclisia subcordata (Oliv), An Underutilized Medicinal Plant in Nigeria. Plant Science Today, 10(3): 260-268 https://doi.org/10.14719/pst.2292
  12. Ogunlakin AD, Oyindamola Esther Awosola, Gbenga Temidayo Ajayi, Oluwafemi Adeleke Ojo (2023) Phytochemistry of Medicinal Plants Documented for the Treatment of Low Sperm Count in Oluponna, Nigeria. Pharmacognosy Journal 15(2):1-9.
  13. Ogunlakin AD, Mubo Adeola Sonibare, Oluwafemi Adeleke Ojo (2023). Review on Effect of Medicinal Plants on Female Reproductive System. Tropical Journal of Natural Product Research 7(3): 2473-2483.
  14. Ogunlakin AD, Mubo A. Sonibare, Oloruntoba E. Yeye, Gideon Ampoma Gyebi, Damilare IyinKristi Ayokunle, Olayemi Elizabeth Arigbede, Adeshina Isaiah Odugbemi, Almas Jabeen, Syeda Farah Shah, Farzana Shaheen, Oluwafemi Adeleke Ojo (2023) Isolation and Characterization of Novel Hydroxyflavone from Kigelia africana Fruit Ethyl Acetate Fraction against CHO 1 and HeLa Cancer Cell Lines: In vitro and in silico studies. Journal of Molecular Structure, 2023, 135180. https://doi.org/10.1016/j.molstruc.2023.135180.
  15. Oluwafemi Adeleke Ojo, Damilare Emmanuel Rotimi, Adebola Busola Ojo, Ogunlakin AD, Basiru Olaitan Ajiboye (2023) Gallic acid protects against oxidative stress and neuro inflammation and alleviate neurotransmitters level in cadmium chloride-induced neurotoxicity in Wistar rats. Scientific Reports, 13:1577. https://doi.org/10.1038/s41598-023-28893-6.
  16. Ogunlakin AD and Mubo A. Sonibare (2022). Review on Phytochemistry and Biological Activities of Tetracera species. Trends in Phytochemical Research, 6(4): 339-352
  17. Ojo, O.A., Ogunlakin AD., Iyobhebhe, M., Olowosoke, C.B., Taiwo, O.A., Akinola, A., Fadiora, D., Odugbemi, A.I., Gyebi, G.A., Nwonuma, C.O. and Ojo, A.B. (2022). Computer aided and experimental study of cinnamic acid analog for oxidative stress treatment: The therapeutic validations. Informatics in Medicine Unlocked, 35: 101137.
  18. Oluwafemi Adeleke Ojo, Susan Grant, Jennifer Chidubem Amanze, Abosede Itunuoluwa Oni, Adebola Busola Ojo, Tobiloba Christiana Elebiyo, Olabisi T. Obafemi, Damilare Iyinkristi Ayokunle, Ogunlakin AD (2022) Annona muricata L. peel inhibits carbohydrate metabolizing enzymes and reduces pancreatic β-cells, inflammation, and apoptosis via upregulation of PI3K/AKT genes. PLOSOne.
  19. Mubo A. Sonibare, Taiwo R. Onifade, Ogunlakin AD, Opeyemi J. Akinmurele, Abayomi S. Adebodun (2022). Microscopic Evaluation and Antioxidant Activity of Glyphaea brevis (Spreng.) Monach. (Family Tiliaceae). Free Radicals and Antioxidants 12(1):19-23.
  20. Ogunlakin AD, Sonibare MA, Almas Jabeen, Syeda FS, Farzana S (2021). Antioxidant and Anti-Proliferative Studies on Constituents of Kigelia africana (Lam.) Benth. Tropical Journal of Natural Product Research 5(3): 570-575 
  21. Ogunlakin AD, Sonibare MA, Almas Jabeen, Syeda FS, Farzana S (2020). Antiproliferative and ameliorative effects of Tetracera potatoria and its constituent. Advances in Traditional Medicine (ADTM). https://doi.org/10.1007/s13596-020-00511-0
  22. Ogunlakin AD and Sonibare MA (2019). Ethnobotanical survey of medicinal plants used as remedy for female infertility and menstrual disorder in Southwestern Nigeria. Nigerian Journal of Pharmaceutical Research 15(2): 27-36
  23. Sonibare MA and Ogunlakin AD (2016). Antidiabetic and antioxidant effects of methanol extract and fractions of Glyphaea brevis (Spreng.) Monachino in alloxan-induced diabetic rats. West African Journal of Pharmacy 27. 1: 42-53.
  24. Adesanya EO, Oyesiku OO, Adesanya OO, Ogunlakin AD, Odugbemi AI, Egieyeh SA (2023). Phytochemical components and GC–MS analysis of Petiveria alliaceae L. fractions and volatile oils. Physical Sciences Reviews. 2023 Apr 17(0). https://doi.org/10.1515/psr-2022-0311.
  25. Enitan Omobolanle Adesanya and Ogunlakin AD (2022) Potentials of African Botanicals in Management of Staphylococcal Infections. In: Staphylococcal Infections – Recent Advances and Perspectives. IntechOpen Limited, London. http://doi.org/10.5772/intechopen.108351