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Christian Eseigbe IMAFIDON

Assistant Professor
college of Health Sciences (COHES)
Physiology Programme

A Faculty member in the College of Health Sciences. He once served as the Acting Dean, Faculty of Basic Medical and Health Sciences and is currently the Head of Physiology programme. He has served in various administrative capacities within the College of Health Sciences, and Bowen University at large. Dr. Imafidon is a lecturer, basic medical and clinical researcher with special interest in Applied Physiology, Genomics and Nephrogenomics. He is an AREF Fellow and a recipient of several research grants.

Education
  • Clinical Research Fellowship (2021) London School of Hygiene and Tropical Medicine (Genomics and Nephrogenomics)
  • Ph.D. (2019) Obafemi Awolowo University, Ile-Ife, Osun State, Nigeria (Applied Physiology)
  • M.Sc. (2016) Obafemi Awolowo University, Ile-Ife, Osun State, Nigeria (Physiology)
  • B.Sc. (2007) Ambrose Alli University, Ekpoma, Edo State, Nigeria (Human Physiology)
Research

Applied Physiology and clinical research with special interest in shifting the paradigm to a more efficacious and racial specific treatment as well as management strategies for sub-Saharan populations through a blend of genomics tool and novel biochemical assay techniques. This also takes into cognizance, assessment of alternative diagnostic medium to blood and experimental medicine, leading to translational research that should culminate in “policy development and implementation research”.

Institutional Service
  • Acting Dean / Senior Assistant Provost, Faculty of Basic Medical and Health Sciences
  • Head of Physiology Programme
  • Examination Officer
  • Level Adviser
  • Postgraduate examiner and supervisor
  • Chairman, Physiology Curriculum Review Committee
  • Chairman, College of Health Sciences, Research Ethics Committee
  • Member, Bowen University, Research Ethics Committee
  • Member, COHES quality assurance unit
  • Member, Bowen University Mock Accreditation Committee
  • Member, Faculty Board of Examiners
  • Member, COHES Board of Examiners
Professional Service
  • Reviewer, Early Career Research Grant Applications for Post Graduate Students and Members of Staff
  • Reviewer, Bowen University Research Ethics Policy
  • Mentorship for pre-clinical and medical students
Selected Publications
  1. Imafidon C.E., Akomolafe R.O., Oke G.O. (2020). Saliva renal function biomarkers as alternatives to plasma concentrations in obesity-induced kidney injury. Obesity Medicine, Elsevier. 17 (2020) 100195. https://doi.org/10.1016/j.obmed.2020.100195
  2. Oboh M.A., Omoleke S.A., Imafidon C.E., Ajibola O., Oriero E.C., Amambua-Ngwa A (2020). Beyond SARS-CoV-2: Lessons that African government can apply in preparation for possible future epidemics. Journal of Preventive Medidicine and Public Health, 10: 307 – 310. https://doi.org/3961/jpmph.20.259
  3. Imafidon C.E., Akomolafe R.O., Eluwole O.A., Adekunle I.A., Agbaje R.A. (2019). Aqueous garlic extract improves renal clearance via vasodilatory/antioxidant mechanisms and mitigated proteinuria via stabilization of glomerular filtration barrier. Clinical Phytoscience, Springer. 5(27): 1–13. https://doi.org/10.1186/s40816-019-0118-y
  4. Imafidon C.E., Akomolafe R.O. (2019). Obesity-induced renal injury is associated with oxidative stress via ischemia reperfusion injury. Obesity Medicine, Elsevier. 14 (2019) 100093. https://doi.org/10.1016/j.obmed.2019.100093
  5. Onwuemene N.J., Imafidon C.E., Ayoka A.O. (2019). Curcuma longa normalized cimetidine-induced pituitary-testicular dysfunction: Relevance in nutraceutical therapy. Animal Models and Experimental Medicine, Wiley. 2019(1): 1-10. https://doi.org/10.1002/ame2.12081
  6. Ogundipe O.J., Olaleye R.O., Imafidon C.E., Olukiran O.S., Akinpelu O.F., Sanusis A.J., Oyerinde A., Oyelade R.O. (2019). Aqueous and Methanolic extract of Ocimum gratissimum (Linn.) leaf reversibly normalizes the antioxidant activities of rats with gentamicin-induced liver injury. International Journal of Research and Scientific Innovation. 6(9): 135 – 143.
  7. Oke G.O., Abiodun A.A., Imafidon C.E., Monsi B.F. (2019). Zingiber officinale (Roscoe) mitigates CCl4-induced liver histopathology and biochemical derangements through antioxidant, membrane-stabilizing and tissue-regenerating potentials. Toxicology Reports, Elsevier. 6: 416 – 425. https://doi.org/10.1016/j.toxrep.2019.05.001
  8. Alabi Q.K., Imafidon C.E., Akomolafe R.O. (2019): Kolaviron mitigates proteinuria and potentiates loop diuresis in Wistar rats: Relevance to normal renal function. Journal of Complementary Medicine Research. 10(1): 58 – 67. https://doi.org/10.5455/jcmr.20190112122816
  9. Olukiran O.S., Akomolafe R.O., Ilesanmi O.S., Imafidon C.E., Alabi Q.K. (2019). Proteinuria in relation to age-dependent changes in plasma and urine concentrations of some electrolytes and hematological indices in Wistar rats. Veterinary and Animal Science, Elsevier. 12 (2019) 100048. https://doi.org/10.1016/j.vas.2019.100048
  10. Oke G.O., Imafidon C.E., Adekunle I.A. (2018). Sub-chronic oral propylene glycol administration sustained normal liver function and histology: A suitable alternative vehicle for hydrophobic test-compounds. Progress in Medical Sciences. 2(2): 34 – 42. https://doi.org/10.5455/pms.20180810064951
  11. Olukiran O.S., Akomolafe R.O., Ilesanmi O.S., Imafidon C.E., Alabi Q.K. (2018). Age-related changes in urinary protein excretion in relation to indices of renal function in Wistar rats. Animal Models and Experimental Medicine, Wiley. 1 (2018): 1 – 10. https://doi.org/10.1002/ame2.12035
  12. Imafidon C.E., Olaoluwa S.E., Ogundipe D.J., Eluwole A.O., Adekunle I.A., Oke G.O. (2018). Acetonic extract of Vernonia amygdalina (Del.) attenuates Cd-induced liver injury: Potential application in adjuvant heavy metal therapy. Toxicology Reports, Elsevier. 5: 324 – 332. https://doi.org/10.1016/j.toxrep.2018.02.009
  13. Adekunle I.A., Imafidon C.E., Oladele A.A., Ayoka A.O. (2018). Ginger polyphenols attenuate cyclosporine-induced disturbances in kidney function: Potential application in adjuvant transplant therapy. Pathophysiology, Elsevier. https://doi.org/10.1016/j.pathophys.2018.02.001
  14. Akomolafe R.O., Imafidon C.E., Olukiran S.O., Oladele A.A., Akanji B.O. (2017). Sub-acute administration of lower doses of nicotine caused sex-dependent improvement of renal function in Wistar rats. Toxicology Reports, Elsevier. 4 (2017) 535 – 542. http://dx.doi.org/10.1016/j.toxrep.2017.10.001
  15. Olaleye R.O., Akomolafe R.O., Imafidon C.E, Ogundipe D.J., Olukiran S.O., Oladele A.A (2017). Treatment with methanolic extract of Ocimum gratissimum (Linn.) leaf reversibly normalizes urine protein-creatinine ratio in Wistar rat model of gentamicin-induced kidney injury. International Journal of Medicine and Biomedical Research. 5(3): 155 – 171. http://dx.doi.org/10.14194/ijmbr.5.3.7
  16. Ogundipe D.J., Akomolafe R.O., Sanusi A.A., Imafidon C.E, Olukiran O.S., Oladele A.A. (2017). Ocimum graticimum ameliorates gentamicin-induced kidney injury but decreases creatinine clearance following sub-chronic administration in rats. Journal of Evidence-Based Complementary and Alternative Medicine. 2017: 1 – 11. http://dx.doi.org/10.1177/2156587217691891
  17. Imafidon C.E., Akomolafe R.O., Oladele A.A. (2016). Sexually dimorphic proteinuria in Wistar rats: Relevance to clinical models. Pathophysiology, Elsevier. 23(2016): 51 – 59.  http://dx.doi.org/10.1016/j.pathophys.2016.02.001
  18. Ogundipe O.J., Akomolafe R.O., Sanusi A.A., Imafidon C.E., Olukiran O.S., Ayowole O.A. (2016). Effects of two weeks administration of Occimum gratissimum leaf on feeding pattern and markers of renal function in rats treated with gentamicin. Egyptian Journal of Basic and Applied Sciences, Elsevier. 3(2016): 219 – 231. http://dx.doi.org/10.1016/j.ejbas.2016.07.002
  19. Akomolafe R.O., Imafidon C.E., Olukiran S.O., Oladele A.A., Akande O.A. (2016). Livolin forte ameliorates cadmium-induced kidney injury in Wistar rats. Serbian Journal of Experimental and Clinical Research. 17(2): 107 – 116. http://dx.doi.org/10.1515/SJECR-2016-0033
  20. Akomolafe R.O., Olukiran S.O., Imafidon C.E., Ayannuga O.A., Oyekunle J.A., Akanji B.O., Oladele A.A. (2016). Effects of chronic copper sulphate administration on feeding pattern and markers of renal and liver functions of Wistar rats. Fiziologia. 2016.26.1(89): 13 – 19.
  21. Ayoka O.A., Ojo O.E., Imafidon C.E., Ademoye K.A., Oladele A.A. (2016). Neuro-endocrine effects of aqueous extract of Amaranthus viridis (Linn.) leaf in male Wistar rat model of cyclophosphamide-induced reproductive toxicity. Toxicology Reports, Elsevier. 3(2016): 608 – 619. http://dx.doi.org/10.1016/j.toxrep.2016.07.007
  22. Imafidon C.E., Olatoye T.R., Bamidele F.S., Ojo O.E., Ademoye K.A. (2016). Cadmium-induced testicular toxicity, oxidative stress and histopathology in Wistar rats: Sustained effects of Polyphenol-rich extract of Vernonia amygdalina (Del.) leaf. Journal of Interdisciplinary Histopathology. http://dx.doi.org/10.5455/jihp.20160618041629
  23. Ayoka A.O., Ademoye K.A., Imafidon C.E., Ojo O.E., Oladele A.A. (2016). Aqueous extract of Allium sativum (Linn.) bulbs ameliorated pituitary-testicular injury and dysfunction in Wistar rats with Pb-induced reproductive disturbances. Macedonian Journal of Medical Sciences. http://dx.doi.org/10.3889/oamjms.2016.039
  24. Imafidon C.E., Akomolafe R.O., Sanusi A.A., Ogundipe O.J., Olukiran O.S., Ayowole O.A. (2015). Amelioration of cadmium-induced nephropathy using polyphenol-rich extract of Vernonia amygdalina (Del.) leaves in rat model. Macedonian Journal of Medical Sciences. 3(4): 567 – 577. http://dx.doi.org/10.3889/oamjms.2015.120
  25. Imafidon C.E., Akomolafe R.O., Sanusi A.A., Ogundipe O.J., Olukiran O.S., Ayowole O.A. (2015). Polyphenol-rich extract of Vernonia amygdalina (Del.) leaves ameliorated cadmium-induced alterations in feeding pattern and urine volume of male Wistar rats. Journal of Intercultural Ethnopharmacology. 4(4): 284 – 292. http://dx.doi.org/10.5455/jice.20151107021034
  26. Akomolafe R.O., Olukiran S.O., Imafidon C.E., Ayannuga O.A., Oyekunle J.A., Akanji B.O., Oladele A.A. (2014). A study of two weeks administration of copper sulphate on markers of renal function and feeding pattern of Wistar rats. African Journal of Biochemistry Research. 8(9): 158 – 165. http://dx.doi.org/10.5897/AJBR2014.0814