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Oluwafemi OJO

Assistant Professor
college of AGRICULTURE, ENGINEERING AND SCIENCE (COAES)
Biochemistry Programme

Research interests have focused on Phytomedicine, Molecular Toxicology, and Computational models. 

Education
  • Ph.D. Biochemistry (2020) University of Ilorin, Ilorin 
  • MSc. Biochemistry (2015) Ekiti State University, Ado-Ekiti 
  • BSc. Biochemistry (2010) Babcock University, Ilishan-Remo
Research

My Research have centered on the reactive oxygen species, antioxidant, anti-inflammation, and antidiabetic modulation of oxidative stress to tissues and molecular (DNA) damage induced by naturally occurring and environmental compounds. 

Also the role of medicinal plants and natural products in the management of reproductive dysfunction and neurodegenerative diseases have been my focus. Furthermore, computational studies of bioactive compounds isolated and identified from medicinal plants as drug candidates against cancer, diabetes, malaria, and Alzheimer’s diseases have formed part of my research. 

I have paid particular attention to these compounds and established their interactions with some enzymes and their ability to abate cellular oxidative stress using a series of contemporary biochemical indices and markers of oxidative damage to proteins and lipids. 
Specifically, the antioxidants and/or antidiabetic effects of polyphenols, biflavonoids, isoflavonoids, carotenoids and terpenoids identified from certain food substances and some African indigenous medicinal plants have been examined in the presence of naturally occurring, therapeutic and environmental toxicants using spectrophotometric enzyme assays. 

Very recently, efforts have been made to elucidate the molecular mechanisms of action underlying the redox signaling and protective activities of these compounds focusing on specific signal transduction pathways involving transcription and expression of certain proteins like Nrf2/Keap 1, HQO1, HO-1, PI3K/AKT, PPARγ/PI3K/AKT/PTP1B, cFOS/CREB/cAMP/PKA, JAK2/STAT3, and iNOS determined by Western immuno blot, and RT-PCR Techniques. In addition, inflammatory transcription factors and gene expression such as glucose transporter (GLUT 2 and GLUT 4) genes, (IL-1β, TGF-1β, KIM-1, EPO, and CASP 6) as molecular targets have been my focus.  

In addition, I have established using Biochemical and Molecular Biology techniques (MTT assays, flow cytometry, transepithelial electrical resistance (TEER) assay, and RT-qPCR,) the role and relevance of traditional medicinal plant in male infertility in animal models, TM3 Leydig cells and TM4 Sertoli cells using marker factors (inhibin-β, stem cell factor, androgen binding protein, and StAR). 

Results obtained so far verifiable by publications listed indicate that these dietary and plant secondary metabolites have positive modulating and preventive/protective effects on the noxious effects of toxic agents via several mechanisms- antioxidants, metal chelation, scavenging of ROS, attenuation of ROS-induced DNA damage, apoptosis, down-regulation of some transcription factors and endoplasmic reticulum stress proteins and up-regulation of genes.

Institutional Service
  • Member of College of Sciences Student Handbook Committee (Mar 2017 to June 2017)
  • Member of SIWES College of Sciences supervisory committee (July 2012 to Aug 2014)
  • 400 Level Biochemistry Academic Adviser, Bowen University, Iwo (2022/ 2023)
  • Member, Quality assurance committee, Department of Biochemistry, Bowen University (2022- till date)
  • Member, Postgraduate Board committee, Department of Biochemistry, Bowen University (2022- till date)
  • Member, Research committee, Department of Biochemistry, Bowen University (2022- till date)
  • Member of Biochemistry Programme Curriculum Review (Feb 2017 to Sept 2017)
  • Member of Postgraduate Biochemistry Programme Curriculum Review Feb 2017 to Sept 2017)
  • Member, Local organizing committee on International Conference on Sustainable Dairy Production at Bowen University in conjunction with Friesland Campina held on 28th Nov- 1st Dec, 2022.
Professional Service
  • Secretary, Biology and Health Sciences (BHS) Working group, Nigerian Young Academy, 2023- till date.
  • Member, Editorial Board- Journal of Applied Pharmaceutical Sciences (JAPS) (2022-date)
  • Academic Editor, Biomed Research International (Hindawi) (2021- date)
  • Academic Editor, Evidence-Based Complementary and Alternative Medicine (Hindawi) (2021- date)
  • Member, Editorial Board- Journal of Medicinal Plants for Economic Development (JOMPED) (South Africa (2020- date)
  • Member, Editorial Board- Computational Molecular Biosciences (CMB) (China 2021-date)
  • Review Editor-Editorial Board- Frontiers in Pharmacology; Ethnopharmacology Section (2021- till date)
  • Active Reviewer: Scientific Reports, Pharmaceutical Biology, Toxicology Report, Ecotoxicology and Environmental Safety, International Blood Research & Reviews, Tropical Journal of Natural Product Research (Nigeria), Journal of Medicinal Plants for Economic Development (South Africa), Evidence-Based Complementary and Alternative Medicine (eCAM), PLOS One, Biomedical Materials, International Journal of Environmental Health etc.
Selected Publications
  1. Ogunlakin AD, Sonibare MA, Yeye OE, Jabeen A, Shah SF, Ojo OA, Gyebi GA, Ayokunle DI. (2023). Design, Synthesis, and Characterization of Cinnamic Acid Derivatives with Two Novel Acrylohydrazones on HeLa and CHO‑1 Cancer Cell Lines: The Experimental and Computational Perspective. Chemistry Africadoi.org/10.1007/s42250-023-00770-9 [Scopus-Indexed]
  2. Osemwegie OO, Olaniran AF, Folorunsho JO, Nwonuma CO, Ojo OA, Adetunde LA, Alejolowo OO, Oluba OM, Daramola FY. (2023). Preliminary Bibliometrics of Plant-Derived Health Foods over the Last Decade in the Scopus Database. African Journal of Food Agriculture Nutrition and Development, 23(8): 24363-24382. Doi; 10/18697/ajfand.123.22765 [Scopus-Indexed]
  3. Oyenihi OR, George TT, Oyenihi AB, Omotola EO, Ojo OA, Ayeleso AO, Oguntibeju OO. (2023) Health and commercial relevance of Garcinia species: Key scientometric analyses from three decades of research. Plant Science Today, doi.org/10.14719/pst.2396 [Scopus-Indexed]
  4. Ojo OA, Ogunlakin AD, Gyebi GA, Ayokunle DI, Odugbemi AI, Babatunde DE, Ajayi-Odoko OA, Iyobhebhe M, Ezea SC, Akintayo CO, Ayeleso A, Ojo AB and Ojo OO (2023) GC-MS chemical profiling, antioxidant, anti-diabetic, and anti-inflammatory activities of ethyl acetate fraction of Spilanthes filicaulis (Schumach. and Thonn.) C.D. Adams leaves: experimental and computational studies. Frontiers in Pharmacology 14:1235810. doi: 10.3389/fphar.2023.1235810 [Scopus-Indexed].
  5. Ojo OA, Agboola O, Ogunro OB, Rotimi DE, Iyobhebhe M, Elebiyo TC, Ayeni JF, Ojo AB, Odugbemi AI, Egieyeh SA, Oluba OM. (2023). Beet leaf (Beta vulgaris L.) extract attenuates iron-induced testicular toxicity via modulation of redox imbalance, cholinergic, and purinergic dysfunctions, and glucose metabolizing enzymes activities. Heliyon 9(7) e17700. https://doi.org/10.1016/j.heliyon.2023.e17700 [Scopus-Indexed].
  6. Ogunlakin AD, Onifade TR, Gyebi GA, Obafemi BA, Ojo OA. (2023). In silico pharmacology and bioavailability of bioactive constituents from Triclisia subcordata (Oliv), an underutilized medicinal plant in Nigeria Plant Science Today 10(3): 260–268 https://doi.org/10.14719/pst.2292 [Scopus-Indexed].
  7. Olaniran AF, Osemwegie O, Taiwo AE, Okonkwo CE, Ojo OA, Abalaka M, Malomo AA, Bamidele OP, Iranloye YM, Akpor OB, Bamidele OP, Michael T, (2023). Application and acceptability of microbiome in the production process of Nigerian indigenous foods: Drive towards responsible production and consumption. Preventive Nutrition and Food Science 28(2):108-120. Doi: 10.3746/pnf.2023.28.2.108 [Scopus-Indexed]
  8. Ogunlakin AD, Onifade TR, Ojo OA, Adesanya EO, Berena GA, Ayeni PO, Omolekan TO, Fategbe MA, Ogunlakin MA, Ayokunle DI, Sonibare MA. (2023). Antidiabetic Potential of Carica papaya L. and its constituents: From Folkloric Uses to Products Development. Bioactive Compounds in Health and Disease 6(6): 126-144. DOI: https://www.doi.org/10.31989/bchd.v6i6.1108 [Scopus-Indexed]
  9. Ojo OA, Ibrahim HS, Rotimi DE, Ogunlakin AD, Ojo AB. (2023). Diabetes mellitus: from molecular mechanism to pathophysiology and pharmacology. Medicine in Novel Technology and Devices 19 (2023) 100247 doi: 10.1016/j.medntd.2023.100247. [Scopus-Indexed]
  10. Taiwo OA, Dosumu OA, James AS, Ugwor EI, Ojo OA, Dedeke GA, Ademuyiwa O. (2023). Pre-puberty cannabichromene exposure modulates reproductive function via alteration of spermatogenesis, steroidogenesis, and eNOS pathway metabolites. Toxicology Reports. 10 (2023) 690–705doi:https:/doi.org/10.1016/j.toxrep.2023.06.001 [SCOPUS-INDEXED].
  11. Balogun EA, Otolorin AO, Ayeni SD, Rotimi DE, Ojo OA. (2023). Antidiabetic properties of Dioscoreophyllum cumminsii (Stapf) Diels stem bark on streptozotocin‑induced diabetic rats. Comparative Clinical Pathology https://doi.org/10.1007/s00580-023-03482-1 [Scopus-Indexed]
  12. Rotimi DE, Evbuomwan IK, Iyobhebhe, ME, Olaolu TD, Ojo OA. (2023). Pharmacological activities of Cissus populnea in human diseases. Biocatalysis and Agricultural Biotechnology 50(2023) 102719doi:10.1016/j.bcab.2023.102719 [Scopus-Indexed] 
  13. Ogunlakin AD, Awosola OE, Ajayi GT, Ojo OA.  (2023). Review on Phytochemistry of Medicinal Plants Documented for the Treatment of Low Sperm Count in Oluponna, Nigeria. Pharmacognosy Journal. 15(2): 439-446. doi: 10.5530/pj.2023.15 [Scopus Indexed]
  14. Ojo OA, Nwafor-Ezeh PI, Rotimi DE, Iyobhebhe M, Ogunlakin AD, Ojo AB. (2023). Apoptosis, inflammation, and oxidative stress in infertility: A mini review. Toxicology Reports, 10, 448-462Doi.10.1016/j.toxrep.2023.04.006 [Scopus Indexed]
  15. Evbuomwan IO, Alejolowo OO, Elebiyo TC, Nwonuma CO, Ojo OA, Edosomwan EU, Chikwendu JI, Elosiuba NV, Akulue JC, Dogunro FA, Rotimi DE, Osemwegie OO, Ojo AB, Ademowo OG, Adeyemi OS, & Oluba OM (2023): In silico modeling revealed phytomolecules derived from Cymbopogon citratus (DC.) leaf extract as promising candidates for malaria therapy. Journal of Biomolecular Structure and Dynamics, DOI: 10.1080/07391102.2023.2192799. [Scopus-Indexed]
  16. Ojo OA, Oyetayo FL, Oladipo AS, Oluwatosin VO. (2023). Polyphenolic Contents, Free Radical Scavenging Properties, and Enzyme Inhibitory Activities of Acacia nilotica (L.) Delile Seed and Pod Extracts. Vegetos (2023). https://doi.org/10.1007/s42535-023-00599-0 [Scopus-Indexed]
  17. Ogunlakin AD, Sonibare MA, Ojo OA. (2023). Review on Effect of Medicinal Plants on Female Reproductive System. Trop J Nat Prod Res. 7(3):2473-2483. [Scopus Indexed]
  18. Olaniran AF, Okonkwo CE, Iranloye YM, Morakinyo OO, Taiwo AE, Erinle OC, Bamidele OP, Ojo OA, Malomo AA, Osemwegie OO (2023). Fermented gluten-free multi-grain cereal paste development: The role of the orange-fleshed sweet potato (OFSP) as a dietary supplement. Nutirtion and Metabolic Insights 16: 1-11 doi: 10.1177/11786388231155007 [Scopus-Indexed]
  19. Ojo OA, Rotimi DE, Ojo AB, Ogunlakin AD, Ajiboye BO (2023). Gallic acid abates cadmium chloride toxicity via alteration of neurotransmitters and modulation of inflammatory markers in Wistar rats. Scientific Reports 13, Article number: 1577 (2023) doi: 10.1038/s41598-023-28893-6 [Scopus-Indexed]
  20. Ogunlakin AD, Sonibare MA, Yeye OE, Gyebi GA, Ayokunle DI, Arigbede OE, Odugbemi AI, Jabeen A, Shah SF, Shaheen F, Ojo OA. (2023). Isolation and Characterization of Hydroflavanone from Kigelia africanaFruit Ethyl Acetate Fraction against CHO 1 and HeLa Cancer Cell Lines: An in vitro and in silico studies. Journal of Molecular Structure. 1282 (2023) 135180 https://doi.org/10.1016/j.molstruc.2023.135180 [Scopus-Indexed]
  21. Onikanni SA, Lawal B, Fadaka AO, Bakare O, Adewole E, Taher M, Khotib J, Susanti D, Oyinloye BE, Ajiboye BO, Ojo OA, Sibuyi NRS. (2023). Computational and Preclinical Prediction of the Antimicrobial Properties of an Agent Isolated from Monodora myristica: A Novel DNA Gyrase Inhibitor. Molecules 28(4), 1593. https://doi.org/10.3390/molecules28041593 [Scopus-Indexed]
  22. Rotimi DE, Elebiyo TC, Ojo OA. (2023). Therapeutic Potential of Rutin in Male Infertility: Mini review. Journal of Integrative Medicine 21(2): 130-135 doi.org/10.1016/j.joim.2023.01.004 [Scopus-Indexed] 
  23. Adebayo-Gege G, Alicha V, Omayone TO, Nzekwe SC, Irozuoke CA, Ojo OA, Ajayi AF. (2022). Anti-atherogenic and cardio-protective properties of sweet melon (Cucumis melo. L. Inodorus) seed extract on high fat diet induced obesity in male wistar rats. BMC Complementary Medicine and Therapies 22, 334 (2022). https://doi.org/10.1186/s12906-022-03793-w [SCOPUS-INDEXED].
  24. Onikanni SA Lawal B, Bakare OS, Ajiboye BO, Ojo OA, Farasani A, Kabrah SM, Batiha G.E-S, Conte-Junior, CA. (2022). Cancer of the Liver and its Relationship with Diabetes mellitus. Technology in Cancer Research and Treatment, 21: 1-9; DOI: 10.1177/15330338221119743 [SCOPUS-INDEXED].
  25. Akintunde JK, Akomolafe VO, Taiwo OA, Ahmad I, Patel H, Osifeso A, Olusegun AO, Ojo OA. (2022).Antihypertensive activity of Roasted cashew nut in mixed petroleum fractions-induced hypertension: An in vivoand in silico approaches. Heliyon 8(12) e12339. Doi: 10.1016/j.heliyon.2022.e12339 [Scopus-Indexed] 
  26. Ojo OA, Ogunlakin AD, Iyobhebhe M, Olowosoke CB, Taiwo OA, Akinola A, Fadiora D, Odugbemi AI, Gyebi GA, Nwonuma CO, Ojo AB, Ojo OO. (2022). Computer Aided and Experimental study of cinnamic acid analog for oxidative stress treatment: The therapeutic validations. Informatics in Medicine Unlocked 35 (2022) 101137. Doi: 10.1016/j.imu.2022.101137 [Scopus-Indexed) 
  27. Ojo OA, Grant S, Amanze JC, Oni AI, Ojo AB, Elebiyo TC, Obafemi TO, Ayokunle DI, Ogunlakin AD. (2022) Annona muricata L. peel extract inhibits carbohydrate metabolizing enzymes and reduces pancreatic β-cells, inflammation, and apoptosis via upregulation of PI3K/AKT genes. PLoS ONE 17(10): e0276984. https://doi.org/10.1371/journal.pone.0276984 [SCOPUS-INDEXED]
  28. Nwonuma CO, Nwatu VC, Mostafa-Hedeab G, Adeyemi OS, Alejolowo OO, Ojo OA, Adah SA, Awakan OJ, Okolie CE, Asogwa NT, Inemesit UA, Egharevba GO, Aljarba NH, Alkahtani S, Batiha G.E-S. (2022). Experimental validation and molecular docking to explore the active components of cannabis in testicular function and sperm quality modulations in rats. BMC Complementary Medicine and Therapies 22:227, https://doi.org/10.1186/s12906-022-03704-z [SCOPUS-INDEXED].
  29. Ajiboye BO, Oyinloye BE, Ojo OA, Lawal OE, Jokomba YA, Balogun BA, Adeoye AO, Ajuwon OR(2022). Effect of Flavonoid-Rich Extract from Dalbergiella welwitschii Leaf on Redox, Cholinergic, Monoaminergic, and Purinergic Dysfunction in Oxidative Testicular Injury: Ex Vivo and In Silico Studies. Bioinformatics and Biology Insights, 16: 1–17, doi: 10.1177/11779322221115546 [SCOPUS-INDEXED].
  30. Elebiyo TC, Rotimi DE, Owen IK, Maimako RF, Iyobhebhe M, Ojo OA, Oluba OM, Adeyemi OS (2022). Reassessing vascular endothelial growth factor (VEGF) in anti-angiogenic cancer therapy. Cancer Treatment and Research Communications, 32C (2022) 100620 doi.org/10.1016/j.ctarc.2022.100620 [SCOPUS-INDEXED]
  31. Ojo OA, Iyobhebhe M, Atunwa B, Ojo AB. (2022). A review on the ethnobotanical, phytochemistry, and pharmacological activities of Aristolochia Longa L. Karbala International Journal of Modern science 8(3): 375-382 https://doi.org/10.33640/2405-609X.3245 [SCOPUS-INDEXED]
  32. Ojo AB, Gyebi G, Alabi O, Iyobhebhe M, Nwonuma CO, Ojo OA. (2022). Syzygium aromaticum (L.) Merr. & L.M.Perry mitigates iron-mediated oxidative brain injury by modulation of redox imbalance, cholinergic and purinergic dysfunctions, and glucose metabolizing enzymes activities. Journal of Molecular Structure 1268C (2022) 133675 doi: 10.1016/j.molstruc.2022.133675 [ISI/SCOPUS-INDEXED].
  33. Ojo AB, Oni AP, Rotimi DE, Iyobhebhe M, Adeniji PO, Talabi Y, Ojo OA (2022). Nanoparticles application as a therapeutic strategy for diabetes mellitus management. Ukrainian Biochemical Journal 94(2): 15-23 doi: https://doi.org/10.15407/ubj94.02.015 [SCOPUS-INDEXED].
  34. Rotimi DE, Ojo OA, Olaolu TD, Adeyemi OS. (2022). Exploring Nrf2 as a therapeutic target in testicular dysfunction. Cell and Tissue Research 390(1): 23-33 https://doi.org/10.1007/s00441-022-03664-3 [ISI/SCOPUS-INDEXED].
  35. Johnson TO, Adegboyega AE, Ojo OA, Yusuf AJ, Iwaloye O, Ugwah-Oguejiofor CJ, Asomadu RO, Chukwuma IF, Ejembi SA, Ugwuja EI, Alotaibi SS, Albogami SM, Batiha GE-S, Rajab BS and Conte-Junior CA (2022) A Computational Approach to Elucidate the Interactions of Chemicals from Artemisia annua Targeted Toward SARS-CoV-2 Main Protease Inhibition for COVID-19 Treatment. Frontiers in Medicine, 9:907583. doi: 10.3389/fmed.2022.907583 [ISI/SCOPUS-INDEXED].
  36. Taiwo OA, Dosumu OA, Akomolafe OV, Oni EO, Adefuye AB, Shofunde AA, Samuel OM, Ojo OA. (2022). Occupational Exposure in automobile repair workshops: Toxicological effects of contaminated soil in Wistar rats. Toxicology Research 11(3): 537-546 doi.org/10.1093/toxres/tfac030 [ISI/SCOPUS – INDEXED].
  37. Fadaka AO, Taiwo OA, Dosumu OA, Owolabi OP, Ojo AB, Sibuyi NRS, Ullah S, Madiehe AM, Klein A, Meyer M, Ojo OA (2022). Computational Prediction of Potential Drug-like Compounds from Cannabis sativa Plant Extracts Targeted Towards Alzheimer Therapy. Journal of Molecular Liquids 119393 doi.org/10.1016/j.molliq.2022.119393 [ISI/SCOPUS – INDEXED].
  38. Ojo OA, Adeyemo TR, Rotimi D, Batiha GE-S, Mostafa-Hedeab G, Iyobhebhe EB, Elebiyo TC, Atunwa B, Ojo AB, Lima CMG, Conte-Junior CA. (2022). Anticancer properties of curcumin against colorectal cancer: a review. Frontiers in Oncology, 12:881641 doi: 10.3389/fonc.2022.881641 [ISI/SCOPUS – INDEXED].
  39. Ojo OA, Amanze J, Oni AP, Grant S, Iyobhebhe M, Elebiyo TC, Rotimi D, Asogwa NT, Oyinloye BE, Ajiboye BE, Ojo, AB (2022). Antidiabetic activity of avocado seeds (Persea americana Mill.) in diabetic rats via activation of PI3K/AKT signaling pathway. Scientific Reports 12: 2919, doi: 10.1038/s41598-022-07015-8[ISI/SCOPUS – INDEXED].
  40. Ojo OA, Oni AP, Grant S, Amanze J, Ojo, AB, Taiwo OA, Maimako RF, Evbuomwan IO, Iyobhebhe M, Nwonuma CO, Osemwegie O, Agboola AO, Akintayo CO, Asogwa NT, Aljarba NH, Alkahtani S, Mostafa-Hedeab G, Batiha G.E-S, Adeyemi OS (2022). Antidiabetic activity of Elephant grass (Cenchrus purpureus (Schumach.) Morrone) via activation of PI3K/AkT signaling pathway, oxidative stress inhibition, and apoptosis in Wistar rats. Frontiers in pharmacology 13:845196. doi: 10.3389/fphar.2022.845196 [ISI/SCOPUS – INDEXED].
  41. Osukoya O, Ajiboye BO, Oyinloye BE, Owero-ozeze O, Ojo OA, Kappo, P. (2022). Aqueous extract of Solanum macrocapon Linn leaves abate diabetic cardiomyopathy by attenuating oxidative stress and inflammation in rats. Journal of Food Biochemistry 46(8):e14172. DOI: 10.1111/jfbc.14172 [ISI/SCOPUS – INDEXED].
  42. Ojo OA, Ojo AB, Barnabas M, Iyobhebhe M, Elebiyo TC, Evbuomwan IO, Michael T, Ajiboye BO, Oyinloye BE, Oloyede OI. (2022). Phytochemical properties and pharmacological activities of the genus Pennisetum: A Review. Scientific african 16C:e01132 doi: https://doi.org/10.1016/j.sciaf.2022.e01132 [SCOPUS – INDEXED].
  43. Alejolowo OO, Anointing PE, Nwonuma CO, Awakan OJ, Adeyemi OS, Ojo OA, Evbuomwan IO, Olaniran AF. (2022). Modulatory effect of fermented Tetracarpidium conophorum (African walnut) supplemented diet on cadmium-induced toxicity in rats. Food Research 6(1): 223-232. Doi: https://doi.org/10.26656/fr.2017.6(1).683[ISI/SCOPUS – INDEXED].
  44. Ojo OA, Aruleba RT, Adekiya TA, Sibuyi NR, Ojo AB, Ajiboye BO, Oyinloye BE, Adeola HA, Fadaka AO (2022). Deciphering the interaction of Puerarin with cancer macromolecules: An in silico investigation. Journal of Biomolecular structure and dynamics 40(2): 848-859 doi: 10.1080/07391102.2020.1819425. ISI/
  45. Ojo, OA., Ojo AB, Nwonuma CO, Awakan OJ, Maimako RF, Afolabi BL, Taiwo OA (2022). Puerarin: A Review on the Pharmacological Activity, Chemical Properties and Pharmacokinetics of Main Isoflavonoid. The Natural Products Journal 12(1): e160921187628 DOI: 10.2174/2210315510999201105145149. [SCOPUS – INDEXED]
  46. Khan MI, Bouyahya AH, Hachlafi NE, Menyiy NE, Akram M, Sultana S, Zengin G, Ponomareva L, Shariati MA, Ojo OA, Dall’Acqua S, Elebiyo CT. (2022). Anticancer properties of medicinal plants and their bioactive compounds against breast cancer: a review on recent investigations. Environmental Science and Pollution Research, Doi:10.1007/s11356-021-17795-7  [ISI/SCOPUS – INDEXED]
  47. Dosumu OA, Taiwo OA, Akinloye OA, Obadina AO, Rotimi SO, Owolabi OP, Ojo OA (2022). Implications of Cannabis sativa on serotonin receptors 1B (HTR1B) and 7 (HTR7) genes in modulation of aggression and depression. Vegetos 35(1): 19-25, doi: 10.1007/s42535-021-00308-9 [SCOPUS-INDEXED]
  48. Rotimi D, Amanze JC, Iyobhebhe M, Ojo AB, Ojo OA. (2022). Kolaviron, a Biflavonoid Compound: Pharmacological activity and Therapeutic Efficacy. Current bioactive compounds, 18(5): 21-29, e311221199738. Doi: 10.2174/1573407218666211231121402.
  49. Ajiboye BO, Oyinloye BE, Agboinghale PE, Ojo, O.A. (2022). Hepatoprotective and haematoprotective roles of Gongronema latifolium Benth aqueous extract in alloxan-induced diabetic rats. Biointerface Research in Applied Chemistry 12(1): 537- 546. [ISI/SCOPUS – INDEXED]
  50. Ajiboye BO, Diayi A, Agunbiade SO, Akinyemi AJ, Adewale OB, Ojo OA. (2022).  Ameliorating Activity of Polyphenolic-Rich Extracts of Basella rubra Leaves on Pancreatic β-Cell Dysfunction in Streptozotocin-Induced Diabetic Rats. Journal of Complementary and Integrative Medicine doi: 10.1515/jcim-2020-0304. [ISI/SCOPUS – INDEXED]
  51. Nwonuma C.O, Favours G.O, Rotimi D.E, Alejolowo O.O, Ojo O.A, Afolabi B.L, Irokanulo E.O. (2021). Comparative Modulatory Assessment of the Sperm Quality and Testicular Function by Solvent Fractions of the Cannabis Extract in Rats. Pharmacognosy Journal 13(6) Suppl: 1678-1687 [SCOPUS-INDEXED]
  52. Johnson TO, Ojo OA, Ikiriko S, Ogunkua J, Akinyemi GO, Rotimi DE, Oche J-R, Adegboyega AE. (2021). Biochemical Evaluation and Molecular Docking Assessment of Cymbopogon citratus as a Natural Source of Acetylcholine esterase (AChE)- targeting Insecticides. Biochemistry and Biophysics Reports 28: 101175, doi.org/10.1016/j.bbrep.2021.101175. [ISI/SCOPUS – INDEXED]
  53. Taiwo OA, Dosumu OA, Oni EO, Akomolafe VO, Elazab ST, Qusti S, Alshammari EM, Batiha G.E-S, Ojo OA. (2021). Preclinical Prediction of phytochemicals Identified from Cannabis as Novel inhibitors of TEX 11, DHCR24, and CatSper 1 in Fertility Drug Design. Informatics in Medicine Unlocked, 26 (15) 100747 doi: doi.org/10.1016/j.imu.2021.100747. [SCOPUS – INDEXED]
  54. Ojo OA, Ojo AB, Okolie C, Abdurrahman J, Barbabas M, Evbuomwan IO, Atunwa OP, Atunwa B, Iyobhebhe M, Elebiyo TC, Nwonuma CO, Adegboyega AE, Qusti S, Alshammari EM, Hetta HF, Batiha G.E-S. (2021). Elucidating the interactions of compounds identified from Aframomum melegueta seeds as Promising Candidates for the Management of Diabetes Mellitus: A computational approach. Informatics in Medicine Unlocked, 26 (15) 100720 doi: https://doi.org/10.1016/j.imu.2021.100720. [SCOPUS – INDEXED]
  55. Ojo OA, Adegboyega AE, Johnson GI, Umedum NL, Onuh K, Adeduro MN, Nwobodo VO, Elekan AO, Alemika TE, Johnson TO. (2021). Deciphering the Interactions of Compounds from Allium sativum Targeted Towards Identification of Novel PTP 1B inhibitors in Diabetes Treatment: A Computational Approach. Informatics in Medicine Unlocked 26(15): 100719 doi: https://doi.org/10.1016/j.imu.2021.100719. [SCOPUS – INDEXED]
  56. Kayode OT, Rotimi D, Okoh E, Iyobhebhe M, Kayode AAA, Ojo OA. (2021). Novel Ketogenic Diet Formulation Improves Sucrose-Induced Insulin Resistance in Canton Strain Drosophila melanogaster. Journal of Food Biochemistry, 45(9): e13907. https://doi.org/10.1111/ jfbc.13907. [ISI/SCOPUS – INDEXED]
  57. Obafemi TO, Jaiyesimi KF, Olomola AA, Olasehinde OR, Olaoye OA, Adewumi FD, Afolabi BA, Adewale OB, Akintayo CO, Ojo OA. (2021). Combined effect of metformin and gallic acid on inflammation, antioxidant status, endoplasmic reticulum (ER) stress and glucose metabolism in fructose-fed streptozotocin-induced diabetic rats. Toxicology Reports 8: 1419-1427 https://doi.org/10.1016/j.toxrep.2021.07.011. [ISI/SCOPUS – INDEXED]
  58. Nwonuma CO, Osemwegie OO, Irokanulo EO, Alejolowo OO, Kayode OT, Olaolu TD, Ada AS, Rotimi DE, Maimako RF, Adedayo AS, Ojo OA. (2021). Comparative effects of combined use of alcohol with cannabis and tobacco on testicular function in rats. Toxicology Research, 10(4): 761-770, doi.org/10.1093/toxres/tfab060.[ISI/SCOPUS – INDEXED]
  59. Kayode OT, Rotimi D, Emmanuel F, Iyobhebhe M, Kayode AAA, Ojo OA. (2021). Contraceptive and Biochemical effect of Juice extract of Allium cepa, Allium sativum, and their Combination in Canton-S Fruit Flies. Journal of Food Biochemistry 45(8) e13821 doi:10.1111/jfbc.13821 [ISI/SCOPUS – INDEXED]
  60. Dosumu OA, Bababode AI, Rotimi OS, Akamo AJ, Omotosho OO, Sani LO, Osinuga KT, Taiwo OA, Owolabi OP, Ojo OA. (2021). DMBA-Induced kidney dysfunction: Effects of Supplementary Dietary Vitamin K in rats. Tropical Journal of Natural Products Research 5(5): 917-923. [SCOPUS – INDEXED].
  61. Ojo, O.A., Ojo AB, Taiwo OA, Oluba OM (2021). Novel Coronavirus (SARS-CoV-2) Main Protease: Molecular docking of Puerarin as a Potential inhibitor. Malaysian Journal of Biochemistry and Molecular Biology24(1): 108-114. [SCOPUS – INDEXED]
  62. Obafemi O, Owolabi O, Omiyale O, Afolabi BA, Ojo OA, Onasanya A, Adu IAI, Rotimi D. (2021) Combination of donepezil and gallic acid improves antioxidant status and cholinesterase activity in aluminum chloride-induced dementia in rats. Metabolic Brain Research, doi.org/10.1007/s11011-021-00749-w. [ISI/SCOPUS – INDEXED]
  63. Ojo OA, Ojo AB, Maimako RF, Rotimi D, Iyobhebhe M, Alejolowo O, Nwonuma CO, Elebiyo TC (2021). Exploring the Potentials of Some Compounds from Garcina kola Seeds Towards Identification of Novel PDE-5 inhibitors in Erectile Dysfunction Therapy. Andrologia, 53(7): e14092 doi: https://doi.org/10.1111/and.14092. [SCOPUS – INDEXED]
  64. Ojo OA, Rotimi D, Emmanuel B, Kayode OT, Ojo AB, Alejolowo O, Ajiboye BO, Oluba OM, (2021). Gallic acid protects against cadmium chloride-induced alterations in Wistar rats via the antioxidant defense mechanism. Journal of Pharmacy and Pharmacognosy Research 9(5): 668-676. [SCOPUS – INDEXED]
  65. Dosumu OA, Owolabi OP, Ugbaja RN, Popoola A, Rotimi SO, Taiwo OA, Ojo OA (2021). Administration of Cannabis Causes Alterations in Monoamine Oxidase B and Serotonin Receptor 2c Gene Expressions in Wistar Rats. Acta Facultatis Medicae Naissensis 38(1): 35-46, doi: 10.5937/afmnai38-28134. [SCOPUS – INDEXED]
  66. Ojo OA, Ojo AB, Okolie C, Nwakama MC, Iyobhebhe M, Evbuomwan IO, Nwonuma CO, Maimako RF, Adegboyega A, Taiwo OA, Alsharif KF, Batiha GE. (2021). Deciphering the Functional Roles of Bioactive Compounds in Selected Traditional Medicinal plants against Alzheimer’s diseases via Pharmacophore modeling, Auto-QSAR, and Molecular Docking Approaches. Molecules 26 (7): 1996, doi: 10.3390/molecules26071996. [ISI/SCOPUS – INDEXED]
  67. Ojo OA (2021). Exploring the Potentials of Selected Bioactive Compounds Isolated from Piper guineense Schumach. & Thonn. Leaf Towards Identification of Novel pfDHFR and pfDHODH inhibitors as Anti-malaria agents. Journal of Applied Pharmaceutical sciences 11(4): 153-158. [SCOPUS – INDEXED]
  68. Rotimi D, Ojo OA, Emmanuel B, Ojo AB, Elebiyo TC, Nwonuma CO, Oluba OM (2021). Protective impacts of gallic acid against cadmium-induced oxidative toxicity in the ovary of rats. Comparative Clinical Pathology 30(3): 453-460 doi: 10.1007/s00580-021-03237-w [SCOPUS – INDEXED]
  69. Nwonuma CO, Osemwegie OO, Alejolowo OO, Irokanulo EO, Olaniran AF, Fadugba DO, Opaleke DO, Ojo OA. (2021) Antioxidant and the Ameliorating Effect of Allium cepa (Onion) Fortified Feed against Potassium Bromate Induced Oxidative Damage in Wistar Rats. Toxicology Reports, 8: 759-766, doi: https://doi.org/10.1016/j.toxrep.2021.03.029 [ISI/SCOPUS – INDEXED]
  70. Ekakitie L, Ajiboye BO, Oyinloye BE, Owero-ozeze OS, Onikanni SA, Ojo, OA (2021). Attenuation of diabetic nephropathy in alloxan-induced diabetic rats by Solanum macrocapon linn leaves aqueous extract. Comparative Clinical Pathology 30(2): 173-179. doi: 10.1007/s00580-021-03220-5. [SCOPUS – INDEXED]
  71. Taiwo OA, Dosumu OA, Ugbaja RN, Rotimi SO, Owolabi OP, Ojo OA (2021). Oral administration of marijuana produces alterations in serotonin receptor 3A gene (HTR3A) and electrolyte imbalances in brain of male Wistar Rats. Molecular Biology Research communications 10(1): 5-11 Doi: 10.22099/mbrc.2020.38601.1557 [SCOPUS – INDEXED]
  72. Ojo OA (2021). Puerarin as a potential drug candidate for the treatment of Diabetes mellitus: Molecular docking and Pharmacophore Modelling studies. Biointerface Research in Applied Chemistry 11(2): 8751- 8759 doi.org/10.33263/BRIAC112.87518759. [ISI/SCOPUS – INDEXED]
  73. Ojo OA, Olayide II, Akalabu MC, Ajiboye BO, Ojo AB, Oyinloye BE, Ramalingam M. (2021). Nanoparticles and their Biomedical Applications. Biointerface Research in Applied Chemistry 11(1): 8431-8445, doi.org/10.33263/BRIAC111.84318445. [ISI/SCOPUS – INDEXED]
  74. Ajiboye BO, Oyinloye BE, Essien PE, Onikanni SA, Ojo OA, Kappo AP (2021). Ameliorative potential of Sterculia tragacantha aqueous extract on renal gene expression and biochemical parameters in streptozotocin-induced diabetic rats. Journal of Pharmaceutical Investigation 51 (1): 103-113 doi.org/10.1007/s40005-020-00506-8 [ISI/SCOPUS – INDEXED]
  75. Ajiboye BO, Oyinloye BE, Owero‑ozeze OS, Okesola MA, Ekakitie IL, Ojo OA, Kappo AP (2021). Aqueous extract of Solanum macrocarpon Linn leaves abates hyperglycaemia and expression of glucose transporters gene in alloxan‑induced diabetic rats. Journal of Endocrinological Investigation 44(2): 256-276.doi.org/10.1007/s40618-020-01280-y. [ISI/SCOPUS – INDEXED]
  76. Dosumu OA, Taiwo OA, Akinloye OA, Oni EO, Owolabi OP, Ojo OA. (2020). Time-Course effects of Cannabis sativa on Brain Acetylcholinesterase (AChE) Activity and Expression of Dopa Decarboxylase Gene (DDC). PharmacologyOnline 2: 302-313 [SCOPUS – INDEXED]
  77. Ekakitie IL, Ojo OA, Oyinloye BE, Ajiboye BO. (2020). Antioxidant and Inhibitory Activities of Enzymes Linked to Type-2 Diabetes Mellitus: The novel role of Chrysobalanus orbicularis extract. Iranian Journal of Toxicology 14(3): 179-186. [SCOPUS – INDEXED]
  78. Batiha GE, Alqahtani A, Ojo OA, Shaheen HM, Wasef L, Elzeiny M, Ismail M, Shalaby M, Murata T, Zaragoza-Bastida A, Rivero-Perez N, Beshbishy AM, Kasozi KI, Jeandet P, Hetta HF. (2020). Biological Properties, Bioactive Constituents, and Pharmacokinetics of Some Capsicum spp. And Capsaicinoids. International Journal of Molecular Sciences 21:5179 doi: 10.3390/ijms21155179. [ISI/SCOPUS – INDEXED]
  79. Dosumu OA, Rotimi SO, Akintunde J, Adeleye OO, Sani OL, Omotosho OO, Osinuga KT, Taiwo OA, Ojo OA. (2020). Effects of vitamin K dietary supplementation in pulmonary dysfunction induced by 7, 12, -dimethyl benz[a] anthracene in rat. Journal of Biochemical and Molecular Toxicology DOI:10.1002/jbt.22584 [ISI/SCOPUS – INDEXED]
  80. Okesola MA, Ojo OA, Onikanni SA, Ajiboye BO, Oyinloye BE, Agboinghale BE, Kappo PA (2020). Ameliorative Effect of Gongronema latifolium Leaf Extract on Alloxan-induced Diabetic Cardiomyopathy in Wistar Rats Model. Comparative Clinical pathology 29(4): 865-872 Doi: 10.1007/s00580-020-03134-8. [SCOPUS – INDEXED]
  81. Ojo, OA., Ojo, AB., Ajiboye BO., Imiere, O., Oyinloye, B.E. (2020). Antihyperlipidemic activities and hematological potentials of ethanol extract of Blighia sapida Koenig bark in alloxan-induced diabetic rats. Serbian Journal of Experimental and Clinical Research 21(1): 11-17 Doi: 10.2478/SJECR-2018-0042. [SCOPUS – INDEXED]
  82. Ajiboye BO, Ojo OA, Oyinloye BE, Okesola MA, Adeyonu O, Boligon AA, Kappo AP (2020). Investigation of the in vitro antioxidants of polyphenolic-rich extract of Artocarpus hetereophyllus Lam stem bark as well as its antidiabetic activity in streptozotocin-induced diabetic rats. Journal of Evidence-Based Integrative Medicine 25: 1-13 doi: 10.1177/2515690X20916123 [SCOPUS – INDEXED]
  83. Ojo OA, Okesola MA, Ekakitie L, Ajiboye BO, Oyinloye BE, Agboinghale PE, Onikanni SA (2020). Gongronema latifolium Benth. leaf extract attenuates diabetes induced neuropathy via inhibition of cognitive, oxidative stress and inflammatory responses. Journal of the Science of Food and Agriculture 100(12): 4504-4511 doi: 10.1002/jsfa.10491. [ISI/SCOPUS – INDEXED]
  84. Ojo OA, Osukoya OA, Ekakitie L, Ajiboye BO, Oyinloye BE, Agboinghale PE, Kappo PA (2020). Gongronema latifolium leaf extract modulates hyperglycaemia, inhibits redox imbalance and inflammation in alloxan-induced diabetic nephropathy. Journal of Diabetes and Metabolic disorders 19(1): 469-481 doi: 10.1007/s40200-020-00533-0. [SCOPUS – INDEXED]
  85. Ajiboye BO, Ojo OA, Oyinloye BE, Akuboh O, Okesola MA, Idowu O, Kappo AP (2020). In vitro antioxidant and inhibitory activities of polyphenolic-rich extracts of Syzygium cumini (Linn) Skeels leaf on two important enzymes relevant to type II diabetes mellitus. Pakistan Journal of Pharmaceutical Sciences 33(2): 523-529. [SCOPUS – INDEXED]
  86. Osukoya OA, Nwoye-Ossy M., Olayide I., Ojo OA, Adewale O., Kuku A (2020). Antioxidant activities of peptide hydrolysates obtained from the seeds of Treculia africana Decne (African breadfruit). Preparative Biochemistry & Biotechnology 50(5): 504-510. [SCOPUS – INDEXED]
  87. Ajiboye BO, Ojo OA, Fatoba B, Afolabi OB, Olayide I, Okesola MA, Oyinloye BE (2020). In vitro antioxidant and enzyme inhibitory properties of n-butanol fraction of Senna podocarpa (Guill. and Perr.) leaf. Journal of Basic and Clinical Physiology and Pharmacology, 31(1): 20190123 Doi: 10.1515/jbcpp-2019-0123. [SCOPUS – INDEXED]
  88. Ojo OA, Afon AA, Ojo AB, Ajiboye BO, Okesola MA, Aruleba RT, Adekiya TA, Oyinloye BE. (2019). Spondias mombim L. (Anacardiaceae): Chemical fingerprints, inhibitory activities and molecular docking on key enzymes relevant to erectile dysfunction and Alzheimer’s diseases. Journal of Food Biochemistry, 43(3); e12772 doi: 10.1111/jfbc.12772. [ISI/SCOPUS – INDEXED]
  89. Oyinloye BE, Adekiya TA, Aruleba T, Ojo OA, Ajiboye BO. (2019). Structure based docking studies of GLUT4 towards exploring selected phytochemicals from Somalia xanthocarpum as a therapeutic target for the treatment of cancer. Current Drug Discovery Technologies, 16(4): 406-416 doi: 10.2174/1570163815666180801152110. [SCOPUS – INDEXED]
  90. Afolabi OB, Obajuluwa A, Obajuluwa T, Okiki P, Oloyede OI, Fadaka OA, Ojo OA (2019) Exposure to a 2.5 GHz non-ionizing electromagnetic field alters hematological profiles, biochemical parameters and induces oxidative stress in male Albino rats. Biomedical and Environmental Sciences 32(11): 860-863. [ISI/SCOPUS – INDEXED]
  91. Ajiboye BO, Oyinloye BE, Agboinghal, PE, Ojo OA, (2019). Cnidoscolus aconitifolius (Mill.) I. M. Johnst leaf extract prevents oxidative hepatic injury and improves muscle glucose uptake ex vivo. Journal of Food Biochemistry, 43(12): e13065. DOI: 10.1111/jfbc.13065. [ISI/SCOPUS – INDEXED]
  92. Olugbodi JO, David O, Ojo OA, Akinmoladun AC. (2019). Influence of Glyphaea brevis twig extract on nucleus, tight junctions and expression of inhibin- β, stem cell factor, and androgen binding protein in TM4 Sertoli cells. Asian Pacific Journal Reproduction, 8(4): 157-166. [SCOPUS – INDEXED]
  93. Osukoya O, Fadaka A, Adewale O, Oluloye O, Ojo OA, Ajiboye B, Adewumi D. and Kuku A. (2019). In vitro anthelmintic and antioxidant activities of the leaf extracts of Theobroma cacao L. AIMS Agriculture and Food, 4(3): 568–577. [SCOPUS – INDEXED]
  94. Olugbodi JO, Uzunuigbe EO, David O, Ojo OA. (2019). Effect of Glyphaea brevis twigs extract on cell viability, apoptosis induction and mitochondrial membrane potential in TM3 Leydig cells. Andrologia.51: e13312. https://doi.org/10.1111/and.13312. [ISI/SCOPUS – INDEXED]
  95. Obafemi TO, Onasanya A, Adeoye A, Falode JA, Daniel DJ, Irefo EF, Ojo OA, Fadaka A, Afolabi OB, Awe JO, Omiyale BO. (2019). Protective effect of methanolic and flavonoid-rich leaf extracts of Synsepalum dulcificum (Danielli) on lead-acetate-induced toxicity in Wistar albino rats. Journal of Applied Pharmaceutical Science, 9(05): 065-072. [SCOPUS – INDEXED]
  96. Ojo, AB., Ojo OA., Okesola MA, Ajiboye BO, Oyinloye BE (2019). Garcinia kola extracts improve biochemical markers associated with erectile function: possible applications in clinical treatment? Acta Facultatis Naissenis, 36(1): 15-26 DOI: 10.2478afmnai-2019-0002. [SCOPUS – INDEXED]
  97. Ojo OA, Ojo AB, Oyinloye BE, Ajiboye BO, Anifowose OO, Akawa A, Olaiya OE, Olasehinde OR, Kappo AP. (2019). Ocimum gratissimum Linn. leaves reduce the key enzymes activities relevant to erectile dysfunction in isolated penile and testicular tissues of rats. BMC Complementary and Alternative Medicine, 19-71 DOI: 10.1186/s12906-019-2481-0. [ISI/SCOPUS – INDEXED]
  98. Okesola MA, Ajiboye BO, Oyinloye BE, Ojo OA. (2019). Neuromodulatory effects of ethyl acetate fraction of Zingiber officinale Roscoe extract in rats with lead- induced oxidative stress. Journal of Intergrative Medicine, 17(2):125-131 Doi: 10.1016/j.joim.2019.01.002. [ISI/SCOPUS – INDEXED]
  99. Okesola MA, Ajiboye BO, Oyinloye BE and Ojo OA. (2019). Effect of Zingiber officinale on Some Biochemical Parameters and Cytogenic Analysis in Lead-induced toxicity in Experimental Rats. Toxicology Mechanisms and Methods, 29(4): 255-262 DOI: 10.1080/15376516.2018.1558321. [SCOPUS – INDEXED]
  100. Ajiboye BO, Akalabu MC, Ojo OA, Afolabi OB, Okesola MA, Olayide I, Oyinloye BE (2018). Inhibitory Effect of Ethyl Acetate Fraction of Solanum macrocarpon L. Leaves on Cholinergic, Monoaminergic and Purinergic Enzyme Activities. Journal of Food Biochemistry, 42(6): e12643 doi:10.1111/jfbc.12643. [ISI/SCOPUS – INDEXED]
  101. 101.              Ajiboye BO, Ojo OA, Okesola MA, Oyinloye BE, Kappo AP. (2018). Ethyl acetate leaf fraction of Cnidoscolus aconitifolius (Mill.) I. M. Johnst: antioxidant potential, inhibitory activities of key enzymes on carbohydrate metabolism, cholinergic, monoaminergic, purinergic and chemical fingerprinting. International Journal of Food Properties. 21(1): 1697-1715. [ISI/SCOPUS – INDEXED]
  102. Ajiboye BO, Ojo OA, Okesola MA, Akinyemi AJ, Talabi JY, Idowu OT, Fadaka AO, Boligon AA, de Campos MMA (2018). In vitro antioxidant activities and inhibitory effects of phenolic extract of Senecio biafrae (Oliv and Hiern) against key enzymes linked with type II diabetes mellitus and Alzheimer’s disease. Food Science and Nutrition, 6(7): 1803–1810. https://doi.10.1002/fsn3.749. [SCOPUS – INDEXED]
  103. Ajiboye BO, Ojo OA, Akuboh OS, Okesola MA, Idowu OT, Oyinloye BE and Talabi JY (2018) The Protective Effect of Polyphenol-Rich Extract of Syzygium cumini Leaves on Cholinesterase and Brain Antioxidant Status in Alloxan-Induced Diabetic Rats. Jordan Journal of Biological Sciences. 11(2): 163 – 169. [SCOPUS – INDEXED]
  104. Ojo OA, Afon AA, Ojo AB, Ajiboye BO, Oyinloye BE, Kappo AP. (2018). Inhibitory Effects of Solvent-Partitioned Fractions of Two Nigerian Herbs (Spondias mombin Linn. and Mangifera indica L.) on α-Amylase and α-Glucosidase. Antioxidants, 7 (6): 73 https:// doi.org/10.3390/antiox7060073. [ISI/SCOPUS – INDEXED]
  105. Ojo OA, Ojo AB, Ajiboye BO, Olaiya O, Okesola MA, Boligon AA, de Campos MMA, Oyinloye BE, Kappo AP. (2018). HPLC-DAD Fingerprinting analysis, antioxidant activities of Tithonia diversifolia (Hemsl.) A. Gray Leaves and its inhibition of Key enzymes linked to Alzheimer’s disease. Toxicology Reports, 5: 585-592 https://doi.org/10.1016/j.toxrep.2018.05.003. [ISI/SCOPUS – INDEXED]
  106. Ajiboye BO, Ojo OA, Akuboh OS, Okesola MA, Idowu O, Amuzat AO. (2018). Anti-Hyperglycemic and Anti-Inflammatory activities of polyphenolic-rich extract of Syzygium cumini linn leaves in alloxan-induced diabetic rats. Journal of Evidence-Based Integrative Medicine, 23: 1-8 DOI: 10.1177/2515690X18770630. [SCOPUS – INDEXED]
  107. Talabi J, Adeyemi S, Awopetu S, Ajiboye BO, Ojo OA. (2018). Inhibitory effect of aqueous extracts of raw and roasted Sesamum indicum L. seeds on key enzymes linked to type-2 diabetes (α-amylase and α-glucosidase) and Alzheimer’s disease (acetylcholinesterase and butyrylcholinesterase). Potravinarstvo® Scientific Journal for Food Industry, vol. 12, no. 1, p. 337-346. Doi:10.5219/866. [SCOPUS – INDEXED]
  108. Ojo, OA., Ojo, AB., Awoyinka, OA., Olayide, I., Ajiboye, BO., Oyinloye, BE., Osukoya, OA., Ibitayo AO. (2018). Aqueous extract of Carica papaya Linn roots potentially attenuates Arsenic induced biochemical and genotoxic effects in Wistar rats. Journal of Traditional and complementary Medicine 8(2): 324-334. Doi: 10.1016/j.jtcme.2017.08.001. [ISI/SCOPUS – INDEXED]
  109. Ojo OA., Ojo AB., Ajiboye BO., Olaiya O., Akawa A., Olaoye O., Anifowose OO., Idowu O., Olasehinde O., Obafemi T., Awe J., Oyinloye BE. (2018). Inhibitory effect of Bryophyllum pinnatum (Lam.) Oken leaf extract and their fractions on α-amylase, α-glucosidase and cholinesterase enzyme. Pharmacognosy Journal. 10(3): 497-506 doi: 10.5530/pj.2018.3.82. [SCOPUS – INDEXED]
  110. Ojo O.A., Oyinloye BE., Ojo AB., Ajiboye B.O., OlayideII., Idowu O., Olasehinde O., Fadugba A., Adewunmi F. (2018). Green-route mediated synthesis of silver nanoparticles (AgNPs) from Syzygium cumini (L.) Skeels polyphenolic-rich leaf extracts and investigation of their antimicrobial activity. IET Nanobiotechnology, 12(3): 305-310, doi: 10.1049/iet-nbt.2017.0127. [SCOPUS – INDEXED]
  111. Ajiboye BO, Ojo OA, Adeyonu O, Imiere O, Oyinloye BE, Ogunmodede O. (2018) Ameliorative Activity of Ethanolic Extract of Artocarpus heterophyllus Stem Bark on Alloxan-induced Diabetic Rats.  Adv Pharm Bull, 2018, 8(1), 141-147. doi: 10.15171/apb.2018.017. [SCOPUS – INDEXED]
  112. Ojo, OA., Ojo, AB., Ajiboye, BO., Oyinloye, BE., Akinyemi, AJ., Okesola MA., Boligon, AA., de Campos, MM. (2018). Chromatographic fingerprint analysis, antioxidant properties, and inhibition of cholinergic enzymes (acetylcholinesterase and butyrylcholinesterase) of phenolic extracts from Irvingia gabonensis (Aubry-Lecomte ex O’Rorke) Baill bark. Journal of Basic and Clinical Physiology and Pharmacology 29(2): 217-224. [SCOPUS – INDEXED]
  113. Ojo, A.B., Ojo, O.A., Oyinloye, BE., Ajiboye, BO., Osukoya, O.A., Ogunniran, AO., Fadugba, A., Olasehinde, O. and Idowu, O. (2018) Characterization and Biological Activities of Biosynthesized Silver Nanoparticles from Stems of Blighia sapida K.D. Koenig. Journal of Bionanoscience 12(1): 71-75. [SCOPUS – INDEXED]
  114. Ojo, OA., Ajiboye BO., Imiere OD., Adeyonu O., Olayide II. and Fadaka OA. (2018) Antioxidative Properties of Blighia sapida K.D. Koenig Stem Bark Extract and Inhibitory Effects on Carbohydrate Hydrolyzing Enzymes Associated with Non-Insulin Dependent Diabetes Mellitus.  Pharmacognosy Journal 10(2): 376-383. [SCOPUS – INDEXED]
  115. Ojo, OA., Ojo, AB., Akintayo, C., Ajiboye, BO., Awe, J. and Obafemi, T. (2017) Antioxidant activity and hepatoprotective effect of Ficus asperifolia (Miq.) on carbon tetrachloride-induced hepatic damage in Wistar rats. Journal of Pharmaceutical Sciences and Research, 9(12): 2376-2381. [SCOPUS – INDEXED]
  116. Ojo, OA., Ajiboye, BO., Ojo, AB., Olayide, II., Akinyemi, AJ., Fadaka, AO., Adedeji, EA., Boligon, AA., de Campos, MM. (2017). HPLC-DAD fingerprinting analysis, antioxidant activity of phenolic extracts from Blighia sapida bark and its inhibition of cholinergic enzymes linked to Alzheimer’s disease. Jordan journal of Biological Sciences 10(4): 257-264. [SCOPUS – INDEXED]
  117. Ojo, O.A., Ojo, A.B., Osukoya, O.A. and Ajiboye, B.O. (2017) Aqueous Extract of Carica papaya Linn Roots Halts Sodium Arsenite-induced Renal Inflammation through inhibiting Adenosine deaminase, 8-Hydroxy-2′-deoxyguanosine, C-Reactive Protein and inducible Nitric Oxide Synthase activity. Serbian Journal of Experimental and Clinical Research, 18(4): 323-330. DOI: https://doi.org/10.1515/sjecr-2017-0029. [SCOPUS – INDEXED]
  118. Ajiboye, B.O., Ojo, O.A., Adeyonu, O., Imiere, O., Fadaka, A. and Osukoya, A. (2017). Ameliorative activity of ethanolic extract of Artocarpus heterophyllus stem bark on pancreatic beta-cell dysfunction in alloxan-induced diabetic rats. Journal of Evidence-Based Complementary and Alternative Medicine 22(4): 538-543. DOI: 10.1177/2156587216685510. [SCOPUS – INDEXED]
  119. Ajiboye, B.O., Ojo, O.A., Aganzi, I.Y., Chikezie, G.S., Fadaka, A.O, Jaiyesimi, K and Olaoye, O. (2017).  Antihyperanaemic and antihyperlipidemic activities of Artocarpus altilis fruit based-diet on alloxan-induced diabetic rats. International Food Research Journal, 24(5): 2133-2139. [SCOPUS – INDEXED]
  120. Ojo, OA., Ojo, AB., Ajiboye B.O., Oyinloye, B.E., Imiere, O, Adeyonu, O. (2017). Ameliorative potentials of Blighia sapida K.D. Koenig bark against pancreatic-cell dysfunction in alloxan-induced diabetic rats. Journal of complementary and Integrative medicine, 14(3) Article number 20160145 doi: https://doi.org/10.1515/jcim-2016-0145. [SCOPUS – INDEXED]
  121. Oyinloye, BE., Osunsanmi FO., Ajiboye, B.O., Ojo, O.A. and Kappo, A.P. (2017). Modulatory effect of methanol extract of Piper guineense in CCl4-induced hepatotoxicity in male rats. International Journal of Environmental Research and Public Health, 14(9): 955; doi:10.3390/ijerph14090955. [ISI/SCOPUS – INDEXED]
  122. Ojo OA., Oyinloye, BE., Ojo, AB., Afolabi, OB., Peters, OA., Olaiya, O., Fadaka, A., Jonathan, J. and Osunlana, O. (2017). Green Synthesis of Silver Nanoparticles (AgNPs) Using Talinum triangulare (Jacq.) Willd. Leaf Extract and Monitoring Their Antimicrobial Activity. Journal of Bionanoscience 11(4): 292-296 doi:10.1166/jbns.2017.1452. [SCOPUS – INDEXED]
  123. Ojo, OA., Ajiboye, BO., Fadaka, A., Taro, P. Shariati, MA. (2017) Nrf2-Keap1 Activation, A Promising Strategy in the Prevention of Cancer. Free Radicals and Antioxidants, 7(1): 01-07. Doi: 10.5530/fra.2017.1.1. URL: http: www.antiox.org /article/51. [GOOGLE SCHOLAR – INDEXED]
  124. Fadaka OA, Ajiboye, BO., Ojo, OA., Adewale, O., Olayide, I., Emuowhochere R. (2017). Biology of glucose metabolization in cancer cells. Journal of Oncological Sciences, 3 (2): 45-51. doi: 10.1016/j.jons.2017.06.002. [GOOGLE SCHOLAR]
  125. Fadaka AO, Ajiboye BO, Olowoyeye AO, Olayide II, Ojo OA (2017) Regulation of Apoptotic and Necroptotic Cell Death in Skin Cancer. J Cancer Biol Res 5(4): 1108. [GOOGLE SCHOLAR-INDEXED]
  126. Fadaka AO, Ojo OA, Osukoya OA, Akuboh O. Ajiboye BO. (2017). Role of p38 MAPK Signaling in Neurodegenerative Diseases: A Mechanistic Perspective. Ann Neurodegener Dis 2(1): 1026. [GOOGLE SCHOLAR-INDEXED]
  127. Oyetayo, FL. And Ojo, OA. (2017).  Dennettia tripetala seeds inhibiting ferrous sulfate-induced oxidative stress in Rat tissues in vitro. Oxidants and antioxidants in Medical Sciences. DOI: 10.5455/oams.110417. [GOOGLE SCHOLAR-INDEXED]
  128. Ojo, AB., Adanlawo, IG. And Ojo, OA. (2017). Efficacy of saponins from Helianthus annuus roots on Normoglycemic, antiperoxidative and antihyperlipidemic effects in alloxan-induced diabetic rats. International Journal of pharmacognosy and phytochemical research 9(1): 83-88. [GOOGLE SCHOLAR-INDEXED]
  129. Ojo, OA., and Ojo, AB. (2016). Inhibitory Activity of Tithonia diversifolia (Hemsl.) A. Gray leaves on Some Pro-Oxidants Induced Oxidative Stress in Rat Brain. Toxicology International 23(3):  254-259 DOI:10.22506/ti/2016/v23/i3/146719. [SCOPUS – INDEXED]
  130. Ojo, AB., Adanlawo, IG. And Ojo, OA. (2016). Ameliorative potentials of saponins from Helianthus annuusroots on hepatoproductive and some kidney function indices of alloxan-induced diabetic rats. PharmacologyOnline 3: 73-79. [SCOPUS – INDEXED]
  131. Ajiboye BO., Muhammad NO and Ojo, OA. (2016). Effect of Rana galamensis–based diet on the activities of some enzymes and histopathology of selected tissues of Albino Rats. Potravinarstvo® Scientific Journal for Food Industry, vol. 10, no. 1, p. 489-493. Doi:10.5219/642. [SCOPUS – INDEXED]
  132. Obafemi TO., Onasanya, A, Olaoye, OA., Afolabi, OB., Awe, OJ., Anadozie, SO., Ojo, OA., Adedeji, E. (2016). In vitro antioxidant activity and High performance liquid chromatography (HPLC) analysis of methanolic extract of Platycerium angolense. International Journal of Pharmacognosy and Phytochemical Research 8(9); 1497-1502. [SCOPUS – INDEXED]
  133. Ajiboye, BO., Ojo, OA., Adeyonu, O., Imiere, O., Olayide, I., Fadaka, A., Oyinloye, BE. (2016). Inhibitory effect of key enzymes relevant to acute type-2-diabetes and antioxidative activity of ethanolic extract of Artocarpus heterophyllus stem bark. Journal of acute disease, 5(5): 423-429. doi: 10.1016/j.joad.2016.08.011. [SCOPUS – INDEXED]
  134. Oyinloye, BE., Ajiboye, B.O., Ojo, O.A. Musa, H.M., Onikanni, SA. and Ojo, A.A. (2016). Ameliorative potential of Aframomum melegueta extract in cadmium-induced hepatic damage and oxidative stress in male Wistar rats. Journal of Applied Pharmaceutical Science, 6 (7): 94-99.  DOI: 10.7324/JAPS.2016.60714. [SCOPUS – INDEXED]
  135. Ojo, OA., Ojo, AB., Ajiboye B.O., Olayide, I and Fadaka, AO. (2016). Helianthus annuus Leaf Ameliorates Postprandial Hyperglycaemia by inhibiting carbohydrate hydrolyzing enzymes associated with Type-2 diabetes.Iranian Journal of Toxicology 7(5): 17-22. [SCOPUS – INDEXED]
  136. Ojo, OA., Ojo, AB., Ajiboye, BO., Akintayo, CO., Oyinloye, BE. And Ojo, AA. (2016). Carbon Tetrachloride-induced oxidative stress in Wistar rat brain: Neurocurative potential of Ficus asperifolia (Miq). Journal of Chemical and Pharmaceutical Sciences 9(3): 1334-1338. [SCOPUS – INDEXED]
  137. Ojo, OA., Ojo, AB., Ajiboye B.O., Fadaka, AO., Imiere OD., Adeyonu, O and Olayide, I. (2016). Protective Influence of Ficus asperifolia Miq Leaf Extract on Carbon tetrachloride (CCL4)-Induced Testicular Toxicity in rat’s Testes. Journal of Applied Pharmaceutical Science, 6 (6): 37-41.  DOI: 10.7324/JAPS.2016.60607. [SCOPUS – INDEXED]
  138. Ajiboye., B.O., Chikezie, G.S., Aganzi, I.Y., Ojo, O.A., Onikanni, S.A., Afolabi, O.B., Anadozie, S and Sobajo, O. (2016). Effect of Artocarpus altilis fruit based-diet on liver and kidney function indices on alloxan-induced diabetic rats. Mediterranean Journal of Nutrition and Metabolism, 9: 23-35. [SCOPUS – INDEXED]
  139. Oyinloye, BE., Ajiboye, B.O., Ojo, O.A. Nwozo, S.O. and Kappo, A.P. (2016). Cardioprotective and antioxidant influence of aqueous extracts from Sesamum indicum seeds on oxidative stress induced by cadmium in Wistar rats. Pharmacognosy Magazine, 12(46): S170-S174. [SCOPUS – INDEXED]
  140. Ojo., OA and Oloyede, OI. (2016). Extracts of Ocimum gratissimum leaves inhibits Fe2+ and sodium nitroprusside induced oxidative stress in rat liver. Journal of Pharmaceutical and Scientific Innovations 5(3) 85-89. DOI:10.7897/2277-4572.05318. [GOOGLE SCHOLAR – INDEXED]
  141. Ojo, OA., Ojo., A.B., Fadaka, AO and Ajiboye B.O. (2016). Antioxidant and Drug detoxification potentials of Ficus asperifolia Miq. Extract in CCl4-Induced Kidney Injuries and Oxidative Damage in Wistar Rats. Advances in Bioresearch 7(5): 162-168. DOI: 10.15515/abr.0976-4585.7.5.162168. [GOOGLE SCHOLAR – INDEXED]
  142. Ojo, OA., Ajiboye B.O., Olayide, I., Fadaka, AO and Olasehinde, O.R. (2016). Ethyl acetate fraction of bark of Bridelia ferruginea Benth. inhibits carbohydrate hydrolyzing enzymes associated with type 2 diabetes (α-glucosidase and α-amylase). Advances in Bioresearch, 7(3): 126-133. DOI: 10.15515/abr.0976-4585.7.3.126133
  143. Ojo, O.A., Ajiboye, B.O., Oyinloye, B.E., Ojo, A.B., and Olarewaju, O.I (2014). Protective Effect of Irvingia gabonensis stem bark extract on Cadmium-Induced Nephrotoxicity in rats. Interdisciplinary Toxicology, 7(4): 208-214. [ISI/SCOPUS – INDEXED]
  144. Ajiboye, B.O. and Ojo, A.O. (2014). Effect of aqueous leaf extract of Senecio biafrae on hyperglycaemic and hematological parameters of alloxan-induced diabetic rats. Pharmacologyonline, 4; 163-169. [SCOPUS – INDEXED]
  145. Ojo, O.A and Ojo, A.B. (2014). Effects of Ethanolic Extract of Alstonia boonei Stem bark on Hematological Indices of Wister Rat. Pharmacologyonline, 4: 136-140. [SCOPUS – INDEXED]
  146. Ojo, O.A., Oyinloye, B.E., Ajiboye, B.O., Ojo, A.B., Habiba, M. and Olarewaju, O.I (2014). Dichlorvos induced oxidative stress in rat brain: Protective effects of Ethanolic extract of Alstonia boonei stem bark. Asian Journal of Pharmaceutics, 8(4):216-221.  [SCOPUS – INDEXED]
  147. Ojo, O.A., Ajiboye, B.O., Oyinloye, B.E. and Ojo, A.B. (2014). Prophylactic effects of Ethanolic extract of Irvingia gabonensis stem bark against Cadmium-induced Toxicity in albino rats. Advances in Pharmaceutics. 8 pages, Vol 2014, Article ID 894610, Hindawi Publishing        Co-operation. [GOOGLE SCHOLAR – INDEXED]
  148. Ojo, O.A., Oyinloye, B.E., Ajiboye, B.O., and Onikanni, S.A (2014). Neuroprotective Mechanism of Ethanolic Extract of Irvingia gabonensis Stem Bark against Cadmium-Induced Neurotoxicity in Rats. British Journal of Medicine and Medical Research, 4 (36):5793-5805. [GOOGLE SCHOLAR – INDEXED]
  149. Ojo, O.A., Ajiboye, B.O., Oyinloye, B.E. and Akintayo, C.O (2014). Prophylactic Effects of Ethanolic Extract of Alstonia boonei Stem Bark Against DDVP-Induced Toxicity in Albino Rats. Journal of Pharmaceutical Biomedical Sciences, 04(07): 650-657. [GOOGLE SCHOLAR – INDEXED]
  150. Ojo, O.A., Oyinloye, B.E., Ajiboye, B.O., Ojo, A.B., Akintayo, C.O. and Okezie, B. (2014). Dichlorvos Induced Nephrotoxicity in Rat Kidney: Protective Effects of Alstonia boonei Stem Bark. International Journal of Pharmacognosy, 1(7): 429-437: DOI: 10.13040/IJPSR.0975-8232. [GOOGLE SCHOLAR – INDEXED]
  151. Oyinloye, B.E., Nwozo, S.O., Amah, G.H., Awoyinka, A.O., Ojo, O.A., Ajiboye, B.O and Tijani, H.A. (2014). Prophylactic Effect of Aqueous Extract of Sesamum indicum Seeds on Ethanol-induced Toxicity in Male Rats. Nutrition Research Practice, 8:1: 54-58. [ISI/SCOPUS – INDEXED]
  152. Ojo, O.A, Oloyede, O.I, Olarewaju, O.I, Akintayo, C.O and Fadaka, A.O. (2014). Effect of Ocimum gratissimum Extract on the Functional Indices of Selected Tissues of Male Wistar Rats. International Journal of Applied Research Technology 3(6): 41-47. [GOOGLE SCHOLAR – INDEXED]
  153. Ojo, O.A. and Akintayo, C.O. (2014). Assessment of Antioxidant Activity of Ficus Asperifolia MiqAqueous Extract – In Vitro Studies. The Journal of Phytopharmacology, 3(1):16-21. [GOOGLE SCHOLAR – INDEXED]
  154. Ojo, O.A., Oloyede, O.I., Tugbobo, O.S., Olarewaju, O.I. and Ojo, A.B. (2014). Antioxidant and inhibitory effect of scent leaf (Ocimum gratissimum) on Fe2+ and sodium nitroprusside induced lipid peroxidation in rat brain in vitro. Advances in Biological Research, 8 (1): 8-17. [GOOGLE SCHOLAR – INDEXED]
  155. Ojo, O.A., Oloyede, O.I., Ajiboye, B.O. and Olarewaju, O.I. (2014). Effects of aqueous extract of Ocimum gratissimum on some hematological parameters of Albino rats. American Chemical Science Journal, 4(1) 74-81. [GOOGLE SCHOLAR – INDEXED]
  156. Ojo, O.A., Oloyede, O.I., Olarewaju, O.I. and Ojo, A.B. (2013). In-Vitro antioxidant activity and Estimation of Total Phenolic Content in Ethyl Acetate Extract of Ocimum gratissimum. Pharmacologyonline, 3; 37-44. [SCOPUS – INDEXED]
  157. Ojo, O.A., Oloyede, O.I., Olarewaju, O.I., Ojo, A.B., Ajiboye, B.O and Onikanni, S.A. (2013). In-Vitro Antioxidant and Free Radical Scavenging Activities of Ocimum Gratissimum. World Journal of Pharmaceutical Research, 2 (6): 1899-1912. [GOOGLE SCHOLAR – INDEXED]
  158. Ojo, O.A., Oloyede, O.I., Olarewaju, O.I. and Ajiboye, B.O.  (2013). Evaluation of Transaminases Activity of Aqueous Extract of Ocimum Gratissimum in the Liver and Kidney of Albino Rats. International Journal of Biological Medical Research, 4 (4):3650-3653. [GOOGLE SCHOLAR – INDEXED]
  159. Ojo, O.A., Oloyede, O.I., Olarewaju, O.I., Ojo, A.B., Ajiboye, B.O and Onikanni, S.A. (2013). Toxicity Studies of the Crude Aqueous Leaves Extracts of Ocimum gratissimum in Albino Rats. IOSR Journal of Environmental Science, Toxicology and Food Technology (IOSR-JESTFT), 6 (4) 34-39. DOI: 10.9790/2402-0643439. [GOOGLE SCHOLAR – INDEXED]